Top 20 Saddest Grey's Anatomy Character Deaths

VOICE OVER: Phoebe de Jeu WRITTEN BY: Saim Cheeda

Grab the tissues—this one hurts. Join us as we revisit the most heartbreaking farewells in Grey's Anatomy history. Our countdown includes Derek Shepherd, George O'Malley, Lexie Grey, Mark Sloan, Denny Duquette, and more beloved characters whose exits shattered us. We also remember Susan Grey's sudden post-op decline, Craig Thomas collapsing in the OR, Doc the Dog's mercy goodbye, Adele Webber's heartbreaking fade, Dylan Young's sacrifice, Samuel Norbert Avery's brief life, and Andrew DeLuca's shocking end. Spoilers ahead! read more...

Top 20 Saddest Grey's Anatomy Character Deaths

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