Man of Steel, meet misery. Welcome to WatchMojo.com, and today we’ll be counting down our picks for the Top 10 Worst Things That Have Ever Happened To Superman. For this list, we’ll be looking at the very worst things, both physical and emotional in nature, to ever happen to this iconic superhero.

Being Superman’s romantic partner has some pretty major downsides. Welcome to WatchMojo.com, and today we’re counting down the Top 10 Worst Things That Happened to Lois Lane. For this list, we’re looking at some of the times throughout her comic book history that Lois Lane’s life became a living hell, mostly thanks to Superman. Lois, maybe it’s time you explored other options.

The worst things that happened to Randy Marsh on "South Park" didn't take his tegridy away.

The worst things that happened to Stewie Griffin will make you feel bad for the evil baby. For this list, we’ll be looking at the most terrible, awful things ever to happen to this seminal character, often at the hands of his friends and family.

The worst things that have happened to Butters Stotch will leave you saying, “Oh, hamburgers.” For this list, we’ll be looking at the worst things that’ve happened to South Park’s most optimistic, yet unfortunate, resident, Leopold Stoch, aka Butters.

It’s a good thing she’s the toughest critter in Bikini Bottom because these are the worst things that happened to Sandy Cheeks. For this list, we’ll be recounting some of the most unfortunate incidents to befall our favorite deep-sea diving land squirrel.

The worst things that have happened to Cricket on Its Always Sunny will make anybody feel lucky by comparison.

If the worst things that happened to Patrick Star proved anything, it’s that being a big pink loser ain’t easy. We’re recounting some of the worst blunders and circumstances from the show and movies ever to befall SpongeBob’s best friend, Patrick. These can be either due to his own buffoonery or just bad luck. WatchMojo ranks the worst things that happened to Patrick Star. What do you think is the worst thing Patrick has endured? Let us know in the comments!

Taking the worst things that have happened to Morty into consideration, we can see why he doesn’t trust Rick. We're looking at the most painful, embarrassing and traumatic things that have happened to the teen during the show’s first three seasons. Since these moments are tied to specific episodes, a spoiler warning is in effect. WatchMojo ranks worst things that have happened to Morty. What do you think is the worst thing that has happened to Morty? Let us know in the comments!

Here's the crankiest punching bag under the sea. Welcome to WatchMojo, and today we're counting down our choices for the Top 10 Worst Things That Happened to Squidward. For this list, we're reluctantly looking at some of the cruel, unusual, and just plain gruesome incidents for SpongeBob's grumpy neighbor and deluded artist, Squidward Tentacles. Fans have complained that the show takes too much delight in Squidward's misery, and they may have a point. Not only are most of these examples hard to stomach, but there will also be spoilers.

Sometimes, even our favorite porous pal can’t catch a break. Welcome to WatchMojo.com, and today we’re counting down our picks for the Top 10 Worst Things That Ever Happened to SpongeBob SquarePants. For this list, we’re reluctantly looking through some of the worst occurrences that have left our favorite little square dude battered, unfairly punished, and even driven to the point of tears. Warning, not only are these moments hard to watch, but they also contain spoilers. Think you know SpongeBob? Be sure to answer the trivia questions in between some of our entries. There’s three in total, and the answers will be revealed at the end of the video. How many can you get right?

Ron may have worse luck, but some bad things have happened to Kim Possible too.

The worst things ever done to Meg from Family Guy still have us cringing. We’ll be looking at some of the most awful things suffered by the eldest Griffin child on Family Guy, Meg, who always seems to get the short end of the stick in the worst of ways. Being told to shut up is the least of it! WatchMojo ranks the worst things ever done to Meg from Family Guy. What do you think is the worst thing that has happened to Meg? Let us know in the comments!

Being the Merc With a Mouth isn’t easy. He just makes it look like it is. Welcome to WatchMojo.com and today we’re counting down the Top 10 Worst Things That Happened to Deadpool. For this list, we’re looking at the times that life was less than kind to Wade W. Wilson, Marvel’s number one fourth wall breaking, regenerating mercenary. Keep in mind that while Deadpool does have a kick-ass healing factor, he still feels pain, so despite his ability to get over these injuries relatively quickly, they’re nonetheless horrific. We’re specifically looking at incidents from the comics, which means his utterly shameful treatment in “X-Men Origins: Wolverine” won’t be on our list.

With great power comes a whole lot of bad luck, apparently. Welcome to WatchMojo.com and today, we’re counting down our picks of the top 10 worst things that have happened to Spider-Man. For this list, we'll be focusing on the most horrible things the wall-crawler has been through in his long comic book history.