As of start of 2006 season.

10. Mike Schmidt
1972-1989
548 Home Runs

9. Reggie Jackson
1967-1987
563 Home Runs

8. Harmon Killebrew
1954-1975
573 Home Runs

7. Mark McGwire
1986-2001
583 Home Runs

6. Sammy Sosa
1989-active
588 Home Runs and counting…

5. Frank Robinson
1956-1976
586 Home Runs

4. Willie Mays
1951-1973
660 Home Runs

3. Barry Bonds
1986-active
708 Home Runs and counting…

2. Babe Ruth
1914-1935
714 Home Runs

1. Hank Aaron
1954-1976
755 Home Runs

According to the Major League Baseball.
* denotes active player

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